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Undergraduate courses

Postgraduate courses

  


Undergraduate Courses

1.Inorganic chemistry

Code: 132/m
Credit hours (2+1)
Position: Pre-pharmacy second semester.

I- Lectures: (1 hours lecture /week, for 15 weeks)
Occurrence, physical and chemical properties of elements and their compounds are examined with emphasis on periodic relationships. Topics include solubility, acid-base, redox reactions, coordination compounds and elemental properties. Laboratory exercises illustrate lecture concepts and provide background for discussion.

II- Practical Part (3 hours section /week, for 15 weeks):
- Identification of acid Radicals of various inorganic anions (7 x3 hr).
- Identification of Basic Radicals of various metal cations (7 x3 hr)


 

2.Mathematics in pharmacy (161/C)

Code 161/m
Credit hours (2+0)
Position: Prepharmacy year, First Semester

Provides the basics of mathematical methods of integration, derivatization, and regression. It also covers the mean value theorem and curve sketching, and systems of linear equations and matrices.



3.Physical chemistry (112/C)

Code 112/m
Credit hours (2+1)
Position: Prepharmacy year, Second Semester

Covers many topics in physical chemistry including gas, liquid and solid states, chemical kinetics, chemical equilibrium, collegative properties of solutions, electrochemistry, colloids, phase equilibria, biophysical systems, transport of ions and molecules through the cell membrane, sound and light in medicine, and physics of diagnostic X-rays.




4.Pharmaceutical organic chemistry (I) :

Code: 231/9
Credit hours (3+1)
Position: First year, First Semester

I- Lectures: (3 hours lecture /week, for 15 weeks)
1 - Introduction, expression of analytical results:
a- Expression of concentration. (1hr)
b- Chemical equilibrium. (2hr)
2- Statistics and data handling. (4hr)
3- Titrimetric methods of analysis:
a- Buffers (1hr), pH (2hr), indicators (1hr), titration curves (3hr),
Acid base titrations (4hr), Pharmaceutical applications (4hr).
b- Complex formation titrations: theory of complex formation (2hr),
Instability constant (2hr), EDTA titrations (4hr), Cyanometric
titrations (2hr) Mercurimetric titrations (2hr), pharmaceutical
applications (2hr).
c- Precipitate formation titrations; solubility product constant (2hr),
Argentometric titrations (3hr), pharmaceutical applications (2hr).
4- Gravimetric methods of analysis (4hr).

II- Practical Part (3 hours section /week, for 15 weeks):
1st week: Introduction to acid – base titrations, Standardization factor,
Equivalence factor Preparation and standardization of 0.1N
NaOH, 0.1 N HCl
2nd week: Determination of:
HCl / Acetic acid mixture
3rd week: Determination of:
- Boric acid / borax mixture.
- Aspirin
4th week: Determination of:
- HCl / NH4Cl mixture
- NH4Cl by Formol titration
5th week: Determination of:
- CO32- / HCO3- mixture
- CaO / CaCO3 mixture
6th & 7th week: Practical Exam
8th week: Introduction to preciptimetry
- Determination of Cl - by Mohr's method.
9th week: Determination of:
- Cl- by Volhard's method
- Cl- / I - by Fajan's method.
10th week: Determination of Cl - / CN – by Volhard – Leibig's method
11th week: Complexometry
- Determination of Ca2+/ Mg2+ mixture (water hardness)
12th week: Determination of metals in water (Complexometry)
-Al3+ (indirect method)
-Cu2+
-Ni 2+
13th week: Determination of Ca2+ by Gravimetry
14th & 15th week: Practical Exam.




5.Pharmaceutical analytical chemistry (II):
 

Code: 212/9
Credit hours (2+1)
Position: First year, second Semester
I- Lectures: (3 hours lecture /week, for 15 weeks)
1- Redox reactions; as one of the titrimetric methods of analysis:
Theoretical basis (2 hr),Standard oxidants and reductants (2 hr), titration curves (2 hr), pharmaceutical applications (5 hr).
2- Electrochemistry:
a- Introduction; theoretical basis, classifications (2 hr), types of the electrical cells (4 hr).
b- Conductometry (3 hr)
c- Potentiometry (4 hr)
3-Water analysis: chemical examination: determination of it’s: hardness, acidity, alkalinity, dissolved gases, metals, nitrate, nitrite and ammonia content (5 hr).
II- Practical Part (3 hours section /week, for 15 weeks):
1st week: Introduction to Redox titration
2nd week: Preparation and standardization of 0.1N KMnO4, K2Cr2O7
3rd week: Determination of FeSO4 , Mno2
4th week : : Determination of:
- H2O 2 , -Ferrocyanide / Ferricyanide
5th week : Prepartion and standardization of 0.05N NA2 S2O3
Determination of phenol .
6th week : Determination of:
- I2 /I- mixture, - Vit.C
7th week: Determination of Iron ammonium citrate
8th & 9th week : EXAM IN REDOX
10th week: Water analysis:
- Acidity & alkalinity of water
- Metals in water
11th week: Hardness of water by:
- Complexometry
- Soda reagent
12th week: Determination of:
- O2 absorbed
- O2 dissolved
13th week: Determination of Cl- in water by conductometry
Determination of nitrate in water

14th & 15th week: EXAM

6.Instrumental analysis

Code: 361 / 9.
Credit hours (2+1)
Position: Second year, First Semester
I- Lectures: (2 hours lecture /week, for 15 weeks)
1- Polarography: one of the electrochemical methods of analysis (4 hr)
2- Spectrophotometry:
a- Interaction of EMR with matter (2hr), Beer's- Lambert’s law (2hr),
Spectrophotometers (2hr).
b- Spectrophotemetric applications to qualitative and quantitative
analysis (2hr).
3- Spectrofluorometry:
Theory of fluorescence (2hr), emission and excitation spectra (4hr),
Applications (2hr)
4- Chromatography:
Classification, theoretical aspects (2hr), paper chromatography (2hr),
TLC (2 hr), GC (2hr) and HPLC (4hr).

II- Practical Part (3 hours section /week, for 15 weeks):
1st week: Introduction to Instrumental Analysis Scanning of
absorption curve for KMnO4 and determination of λmax.
2nd week: Verification of Beer's law for KMnO4 and determination of
the molar absorptivity(ε).
3rd week: Determination of iron colorimetrically.
4th week: Determination of molar absorptivity for UV/VIS absorbing
substances
5, 6th week: Quantitative determination of the components of a binary
mixture.
7th week: Flame Spectroscopy
-Flame photometric determination of Na+ and K+
8th week: Fluorescence Spectroscopy
-Fluorimetric determination of quinine sulfate.
9th week: Potentiometry
-Determination of the concentration of HCl sample by
Potentiometric titration.
10th week: Determination of the dissociation constant of acetic acid
(pKa) by the direct method.
11th week: Determination of dissociation constant of acetic acid by
indirect method (Potentiometric titration)
12th week: Revision
13th - 15th week: Exam

7.Analysis of food and cosmetics:

Code: 532 / 9.
Credit hours (2+1)
Position: Fourth year, Second Semester
I- Lectures: (2 hours lecture /week, for 15 weeks)
1- Introduction Classification of Lipids (5 hr).
2- Analysis of Oil and Lipids (5 hr).
3- Analysis of Milk (10 hr).
4- Analysis of Cosmetics (10hr).

II- Practical Part (3 hours section /week, for 15 weeks):
1st week: Physical examination of milk including color, odour, B.P.,
pH, % acidity
2nd week: Test for preservatives (Salicylic acid, H2O2, Formaline, Borax).
3rd week: - Examination of milk fortified with a) Ascorbic acid (Vit.C), b)
Iron and c) Ca++ .
4th week: Test for raw and Pasteurized milk including test for amylase,
phosphatase and peroxidase enzymes .
5th week: Reductase test, precipitation test and sedimentation test.
6th week: Examination of oil and butter including determination of
Saponification Value.
7th and 8th week : Exam.
9th week : Examination of cosmotic preparations including analysis of
Aluminium, Calcium and Iron.
10th week : report on oil sample.
11th week: spectro photometric determination of coloring matter in
cosmetics.
12th week: revision
13 th & 14 th week : Exams


8.Good manufacturing practice(GMP)

Code: 542/4/9
Credit hours (2+0)
Position: Forth year, Second Semester
بالمناصفة مع قسم الكيمياء التكنولوجيا الادوية
This course provides guidance for prospective laboratory analysts who must juggle the Food and Drug Administration's good manufacturing practices (GMP) rules with rapidly changing analytical technologies. It provides the students with the concepts, techniques, and tools necessary to perform analyses in an FDA-regulated environment, including clear instructions on all major analytical chemical methods-from spectroscopy to chromatography to dissolution.

Lectures: (1 hours lecture /week, for 15 weeks)
- The qualitative determination of pharmaceuticals using spectroscopic techniques.

- Chemistry and Analysis of Food:
This part deals with the chemical classification of food as well as the different method of its analysis especially the instrumental methods that are characterized by accuracy, sensitivity and reproducibility.
 


Postgraduate Courses

1.spectoscopic analysis:

 The acquisition and interpretation of  infrared, nuclear magnetic resonance (NMR) and ultraviolet spectra are taught. Students interpret sets of spectral data, including carbon-13 NMR and mass spectra, from unknown compounds to identify the structures of the compounds.

 

2.  Chromatography
The course discusses the practical application of chromatography with emphasis on liquid chromatography, reviewing the theory and basic principles of chromatography as a separation tool, and techniques of method development and validation.
The course also provides lab experience in the development and validation of the HPLC method for the analysis of pharmaceuticals by evaluating the effects of molecular structures and the selection of columns and mobile phases in the practical development of the HPLC method.

 

 .

3. Drug Stability and reaction kinetics :

this course deals with:

-Reaction Kinetics

-Decomposition pathways of the drugs

-good storage practice in medical stores and hospitals

-stability of polypeptide and proteins ( biotechnology drug)

- physical instability of the drugs

 

 

4. Bioavailability:

this course deals with:

- biopharmaceutics and drug delivery systems

- drug metabolism and drug interaction

- pharmaceutical aspects of clinical trials

- basic pharmacokinetics

-bioequivalence

 

5. pharmaceutical chemistry :

A study of the effect of chemical functional groups on the physiochemical properties, biological activity, kinetics of medicinal agents. Agents affecting the autonomic nervous system are considered in detail. Drugs acting on the central nervous system are discussed. Other topics include cardiovascular agents, diuretics, endocrine hormones, antidiabetic agents, and anti-cancer drugs are discussed in detail.

 

6.-electrochemical analysis :

this course aims to To illustrate the basic principles and applications of modern electroanalytical methods at the advanced level

this course deals with:

I-Potentiometry

   A. Reference Electrodes

   B. Ion-Selective Electrodes

   C. Direct Potentiometric Measurements

   D. Potentiometric Titrations and Applications

 

II-Coulometry and Electrogravimetry

   A. Electrogravimetry

   B. Controlled-Potential Coulometry

   C. Constant-Current Coulometric Titrations

 

III-Amperometric Analysis

  A. Polarography

  B. Modern Voltammetric Techniques

      a. Pulse Volammetry

      b. Fast Linear Sweep Voltammetry

      c. Anodic Stripping Voltammetry

  C. Amperometric Titrations

 

7. –Chemistry and analysis of lipids:

- classification of lipids

-physicochemical properties of lipids

-determination of total lipid concentration and lipid composition using  the instrumental methods of analysis and the chemical methods.

 

8- organic chemistry

 

The structure, nomenclature, stereo-chemistry, properties and reactions of carbon-containing compounds are introduced. The mechanisms of reactions are emphasized.

The structure and properties of multifunctional compounds including amino acids, carbohydrates and steroids are presented.
The concept of stereoisomerism in organic chemistry is systematically studied in simple and complex molecules. The effects of molecular configuration and conformation on organic reactions are emphasized.

 

9-chemistry and analysis of environmental pollutant :

Provide students with the conceptual information, general principles and practical utility of important environmental sampling and analysis techniques most commonly used in environmental research and pollution control.

 

10-analytical chemistry :

This course aims to illustrate the theory and practice of quantitative analysis at the advanced level

This course covers the fundamentals of instrumental methods of analysis, emphasizing spectroscopic, chromatographic techniques.

 

11.Drug Design:

The rational utilization of drug structure-activity relationships in the design of new drugs is considered.

The metabolism of drugs and other foreign compounds is considered. Emphasis is placed on those substances that are of therapeutic importance.

 

12- Selected Topics in the field of  study