Departments >  Pharmaceutical Analytical Chemistry
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Research is a major activity in the department

 Research in the department centers on applications of analytical chemistry to the study of the pharmaceutical sciences including:

a- Colorimetric and Spectrofluorimetric determination of drugs in presence of potential degradation products.
b- Electrochemical analytical techniques ,fabrication of different types of sensors.
c-HPLC  methods using Diod array detector.
d-Densitometric-thin layer chromatography.
e-Chemometric methods for multicomponent analysis.

 

  Departmental Publications

 1-colorimetric and spectrofluorimetric determination of gentamicin and tobramycin in pure, dosage forms and in mixture with dexamethazone .

           A.M.El kosasy ,  M.F.Abdel Ghany, M.F. Ayad , L.E. Abdel Fattah
           Bull. Fac. Pharm. Cairo University ,vol 41, No. 1 (2003)

 2-Spectrophotometric and spectrofuorimetric determination of gentamicin and tobramycin using 1,4-benzoquinone

           A.M.El kosasy ,  M.F.Abdel Ghany, M.F. Ayad , L.E. Abdel Fattah
           Bull. Fac. Pharm. Cairo University ,vol 41, No. 1 (2003)

3- Spectrophotometric determination of some cephalosporins using first derivative of the ratiospectra and pH induced difference spectral methods

Bull. Fac. Pharm. Cairo University ,vol 41, No. 1 (2003)  

 

4-Determination of Hydroxyurea in Capsules and Biological Fluids by Ion-Selective Potentiometry and Fluorimetry

      A.M. El-kosasy
     
journal of AOAC international vol.86, No1,2003

Abstract and full text :

http://www.aoac.org/pubs/JOURNAL/2003/Jan_Feb_03/Determination_of_Hydroxyurea.htm

5-Novel poly (vinyl chloride ) matrix membrane electrodes for determination of phenolic pollutants in waste water

 A.M. El kosasy , S.M. Riad . L.E.Abd El-Fattah , S.Abd El-Kader Ahmad  

        journal of water research      2003

 

 6- Potentiometric determination of polyether ionophores growth promoters in animal feed preparations.

       El-Kosasy,-AM; Abdel-Razek,-SA

       J-Pharm-Biomed-Anal. 20 Jul 2002; 29(4): 585-592

 Abstract and full text :

http://www.sciencedirect.com/science?_ob=GatewayURL&_origin=SilverLinker&_urlversion=4&_method=citationSearch&_volkey=0731%2d7085%2329%23585%234&_version=1&md5=f8b4abc07c23d37618204839fba86111

 

7- Polymeric membrane electrodes for selective determination of the     central nervous system acting drugs fluphenazine hydrochloride  and nortriptyline hydrochloride.

       El-Ragehy,-NA; El-Kosasy,-AM; Abbas,-SS; El-Khateeb,-SZ

Anal-Chim-Acta. 1 Aug 2000; 418(1): 93-100 

       

  Abstract and full text :

 http://www.sciencedirect.com/science?_ob=GatewayURL&_origin=SilverLinker&_urlversion=4&_method=citationSearch&_volkey=0003%2d2670%23418%2393%231&_version=1&md5=b26265e62ca6e615347e089b1c121d38

 

8-Spectrophotometric and spectrofluorimetric determination of cyclophosphamide and its isomer ifosphamide.

    Amer,-MM; Hassan,-SS; El-Fattah,-SAA; El-Kosasy,-AM

       Anal-Lett. Nov 1998; 31(14): 2411-2430

 

 9- Microcoated wire sensors for the determination of anticancer drugs cyclophosphamide and ifosphamide in the presence of their degradates.

Hassan,-SS; Amer,-MM; Abd-El-Fatah,-SA; El-Kosasy,-AM

Talanta. Aug 1998; 46(6): 1395-1403    

 Abstract and full text :

http://www.sciencedirect.com/science?_ob=GatewayURL&_origin=SilverLinker&_urlversion=4&_method=citationSearch&_volkey=0039%2d9140%2346%231395%236&_version=1&md5=01b14f6ee8ff9e6271a8e8aa4ce53af8

    
10- Membrane sensors for the selective determination of fluorouracil.  

        Hassan,-SS; Amer,-MM; El-Fatah,-SAA; El-Kosasy,-AM

        Anal-Chim-Acta. 11 May 1998; 363(1): 81-87 
 

 Abstract and full text :

http://www.sciencedirect.com/science?_ob=GatewayURL&_origin=SilverLinker&_urlversion=4&_method=citationSearch&_volkey=0003%2d2670%23363%2381%231&_version=1&md5=b67b6b28ffecea5a7a7c066176a0b22e

 



 
11- Spectrophotometric and spectrofluorimetric determination of fluorouracil in the presence of its degradation products

Amer-MM; Hassan-SS; Abd-El-Fatah-SA; El-Kosasy-AM

(Journal-of-Pharmacy-and-Pharmacology); 1998; 50(Feb); 133-138